Kudzu Treatment for Alcohol Abuse Full Text View
On the other side of the safety issue, Singh et al. evaluated the protective effects of puerarin from kudzu root against alcohol-induced toxicities. Alcohol withdrawal after 70 days of drinking generated severe withdrawal symptoms including seizure-type EEG activity. Puerarin suppressed the addictionmediated abnormalities but did not affect the inflammation-related abnormalities. “Recently, preclinical studies with animals have shown reductions in alcohol consumption when treated with isoflavones contained in the kudzu root,” said Penetar. “Therefore, the next step in the research was to assess the effects of kudzu extract on different physical, behavioral and cognitive features in humans.”
- They propose that the suppression of alcohol reinforcement produced by kudzu plant compounds is mediated centrally in the brain reward pathway.
- The complete lack of side effects would favor the conduct of such studies.
- For a final session, they took whichever pill they didn’t take the first time.
- Almost 3 in 4 participants had less intense headaches, more than half had fewer headaches, and 1 in 3 had shorter headaches when taking kudzu root.
The compound puerarin is always found in the highest concentration among all the isoflavones, second is daidzin, followed by daidzein. Always make certain that any kudzu root supplement you buy actually contains enough of the active ingredient to be effective. The Lukas study used 500-mg capsules of kudzu extract (NPI-031, Natural Pharmacia Int., Inc., Research Triangle Park, NC) containing sugar beet-based filler and 19% puerarin, 4% daidzin, and 2.0% daidzein.
Might help treat alcoholism
In addition to her work at the exclusive Executive Health clinic in Marbella, Spain, she helps to keep Fit Recovery up to date with emerging research. Kudzu can be purchased with ease online and it won’t break the bank. However, there are a lot of supplements that claim to contain kudzu that are mostly cheap fillers.
- Relapse is when someone resumes drinking in unhealthy ways after a period of recovery.
- Found that dietary genistein maintains a normal Wnt signaling in the colon epithelium of carcinogen-injected mice through regulating the DNA methylation of Sfrp5 promoter.
- More studies would be needed to see if it works the same way in humans.
- A. Several studies have indicated that even recommended amounts of vitamin A might weaken bones and lead to fractures.
Some research shows that milk thistle may help those looking to treat alcohol-related liver disease. It’s important to note that more studies are needed to confirm that the herb enhances liver health. It kudzu for alcohol cravings also cut the number of heavy drinking days and increased the number of days they didn’t drink at all. One is that it raises your blood alcohol levels faster, which means you may feel intoxicated sooner.
David M. Penetar
To our knowledge the present pilot is the first such a study in the world that has systematically evaluated this novel complex in humans. A number of clinical trials in both genders in various disease states have hinted that the ability to produce the human metabolite S-(-)equol from its isoflavone precursor daidzein may hold unique health benefits. Franke et al. cite studies showing that about 60% of vegetarians and Asians produce equol, whereas only about 30% to 35% of omnivores do so. In 2003, David Overstreet and other scientists found the herb to be effective in reducing alcohol intake on rats. Findings show that subjects who took kudzu drank an average of 1.8 beers per session, compared with the 3.5 beers consumed by those who took a placebo.